S10P (p.Ser10Pro) variant of CD80 (P33681)
S10P (p.Ser10Pro) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
S10P (p.Ser10Pro) variant details
- p.Ser10Pro
- ExAC rs771745016
- TOPMed rs771745016
- gnomAD rs771745016
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.03
- MetaLR 0.01
- MetaSVM -0.94
- CADD 3.87
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available