R90W (p.Arg90Trp) variant of CD80 (P33681)
R90W (p.Arg90Trp) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
R90W (p.Arg90Trp) variant details
- p.Arg90Trp
- ExAC rs761204102
- TOPMed rs761204102
- gnomAD rs761204102
- Missense
- Variant Prioritization Score for Impact Estimate 0.457
- REVEL 0.44
- MetaLR 0.42
- MetaSVM -0.09
- CADD 26.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.00018)
- Structural context available