R63P (p.Arg63Pro) variant of CD80 (P33681)
R63P (p.Arg63Pro) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
R63P (p.Arg63Pro) variant details
- p.Arg63Pro
- gnomAD 3-119544780-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.511
- REVEL 0.43
- MetaLR 0.50
- MetaSVM -0.35
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available