R63L (p.Arg63Leu) variant of CD80 (P33681)
R63L (p.Arg63Leu) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
R63L (p.Arg63Leu) variant details
- p.Arg63Leu
- ExAC rs767373131
- TOPMed rs767373131
- gnomAD rs767373131
- Missense
- Variant Prioritization Score for Impact Estimate 0.495
- REVEL 0.41
- MetaLR 0.43
- MetaSVM -0.50
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available