R63H (p.Arg63His) variant of CD80 (P33681)
R63H (p.Arg63His) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
R63H (p.Arg63His) variant details
- p.Arg63His
- cosmic curated COSV51801
- ExAC rs767373131
- TOPMed rs767373131
- gnomAD rs767373131
- Missense
- Variant Prioritization Score for Impact Estimate 0.502
- REVEL 0.41
- MetaLR 0.50
- MetaSVM -0.34
- CADD 25.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available