M81K (p.Met81Lys) variant of CD80 (P33681)
M81K (p.Met81Lys) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
M81K (p.Met81Lys) variant details
- p.Met81Lys
- gnomAD 3-119544726-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0844
- REVEL 0.02
- MetaLR 0.08
- MetaSVM -1.00
- CADD 4.96
- PolyPhen-2 0.01
- SIFT 0.53
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available