M77T (p.Met77Thr) variant of CD80 (P33681)
M77T (p.Met77Thr) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
M77T (p.Met77Thr) variant details
- p.Met77Thr
- TOPMed rs1320277833
- gnomAD rs1320277833
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.07
- MetaLR 0.15
- MetaSVM -1.07
- CADD 14.30
- PolyPhen-2 0.06
- SIFT 0.28
- Most common in the Latino/Admixed American population (allele frequency 0.00026)
- Structural context available