L74P (p.Leu74Pro) variant of CD80 (P33681)
L74P (p.Leu74Pro) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
L74P (p.Leu74Pro) variant details
- p.Leu74Pro
- ExAC rs763700778
- gnomAD rs763700778
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- REVEL 0.50
- MetaLR 0.46
- MetaSVM -0.07
- CADD 26.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available