L28F (p.Leu28Phe) variant of CD80 (P33681)
L28F (p.Leu28Phe) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
L28F (p.Leu28Phe) variant details
- p.Leu28Phe
- gnomAD rs1379920549
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.02
- MetaLR 0.11
- MetaSVM -1.04
- CADD 16.50
- PolyPhen-2 0.75
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available