L25M (p.Leu25Met) variant of CD80 (P33681)
L25M (p.Leu25Met) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
L25M (p.Leu25Met) variant details
- p.Leu25Met
- cosmic curated COSV10507
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.09
- MetaLR 0.15
- MetaSVM -1.01
- CADD 20.50
- PolyPhen-2 0.99
- SIFT 0.03
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available