L23F (p.Leu23Phe) variant of CD80 (P33681)
L23F (p.Leu23Phe) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
L23F (p.Leu23Phe) variant details
- p.Leu23Phe
- ExAC rs770316948
- TOPMed rs770316948
- gnomAD rs770316948
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.08
- MetaLR 0.04
- MetaSVM -1.03
- CADD 11.10
- PolyPhen-2 0.14
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available