L17R (p.Leu17Arg) variant of CD80 (P33681)
L17R (p.Leu17Arg) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
L17R (p.Leu17Arg) variant details
- p.Leu17Arg
- TOPMed rs544665850
- gnomAD rs544665850
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.06
- MetaLR 0.03
- MetaSVM -0.97
- CADD 2.72
- PolyPhen-2 0.01
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available