K88Q (p.Lys88Gln) variant of CD80 (P33681)
K88Q (p.Lys88Gln) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
K88Q (p.Lys88Gln) variant details
- p.Lys88Gln
- ExAC rs771359795
- TOPMed rs771359795
- gnomAD rs771359795
- Missense
- Variant Prioritization Score for Impact Estimate 0.0858
- REVEL 0.03
- MetaLR 0.20
- MetaSVM -0.94
- CADD 1.60
- PolyPhen-2 0.02
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available