I83M (p.Ile83Met) variant of CD80 (P33681)
I83M (p.Ile83Met) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
I83M (p.Ile83Met) variant details
- p.Ile83Met
- gnomAD 3-119544719-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- REVEL 0.19
- MetaLR 0.25
- MetaSVM -0.84
- CADD 23.10
- PolyPhen-2 0.80
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available