H3D (p.His3Asp) variant of CD80 (P33681)
H3D (p.His3Asp) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
H3D (p.His3Asp) variant details
- p.His3Asp
- TOPMed rs1664503554
- gnomAD rs1664503554
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.07
- MetaLR 0.02
- MetaSVM -1.05
- CADD 15.90
- PolyPhen-2 0.28
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available