H37R (p.His37Arg) variant of CD80 (P33681)
H37R (p.His37Arg) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
H37R (p.His37Arg) variant details
- p.His37Arg
- gnomAD 3-119544858-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.02
- MetaLR 0.09
- MetaSVM -1.03
- CADD 14.80
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available