H37L (p.His37Leu) variant of CD80 (P33681)
H37L (p.His37Leu) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
H37L (p.His37Leu) variant details
- p.His37Leu
- gnomAD 3-119544858-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.03
- MetaLR 0.13
- MetaSVM -0.99
- CADD 16.00
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available