G8R (p.Gly8Arg) variant of CD80 (P33681)
G8R (p.Gly8Arg) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
G8R (p.Gly8Arg) variant details
- p.Gly8Arg
- ExAC rs772876009
- gnomAD rs772876009
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.02
- MetaLR 0.02
- MetaSVM -0.94
- CADD 7.76
- PolyPhen-2 0.06
- SIFT 0.44
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available