G8E (p.Gly8Glu) variant of CD80 (P33681)
G8E (p.Gly8Glu) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
G8E (p.Gly8Glu) variant details
- p.Gly8Glu
- cosmic curated COSV51802
- TOPMed rs1048390794
- gnomAD rs1048390794
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.07
- MetaLR 0.04
- MetaSVM -1.01
- CADD 2.25
- PolyPhen-2 0.55
- SIFT 0.48
- Most common in the Latino/Admixed American population (allele frequency 6.7e-05)
- Structural context available