F31L (p.Phe31Leu) variant of CD80 (P33681)
F31L (p.Phe31Leu) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
F31L (p.Phe31Leu) variant details
- p.Phe31Leu
- gnomAD rs1440204200
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- REVEL 0.04
- MetaLR 0.03
- MetaSVM -0.96
- CADD 4.23
- PolyPhen-2 0.01
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available