F20I (p.Phe20Ile) variant of CD80 (P33681)
F20I (p.Phe20Ile) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
F20I (p.Phe20Ile) variant details
- p.Phe20Ile
- ExAC rs749632025
- TOPMed rs749632025
- gnomAD rs749632025
- Missense
- Variant Prioritization Score for Impact Estimate 0.079
- REVEL 0.02
- MetaLR 0.02
- MetaSVM -1.02
- CADD 5.78
- PolyPhen-2 0.04
- SIFT 0.20
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available