E86G (p.Glu86Gly) variant of CD80 (P33681)
E86G (p.Glu86Gly) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
E86G (p.Glu86Gly) variant details
- p.Glu86Gly
- gnomAD 3-119544711-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.127
- REVEL 0.02
- MetaLR 0.11
- MetaSVM -0.98
- CADD 16.60
- PolyPhen-2 0.17
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available