E58V (p.Glu58Val) variant of CD80 (P33681)
E58V (p.Glu58Val) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
E58V (p.Glu58Val) variant details
- p.Glu58Val
- TOPMed rs931956626
- gnomAD rs931956626
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.32
- MetaLR 0.43
- MetaSVM -0.44
- CADD 24.60
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available