E58G (p.Glu58Gly) variant of CD80 (P33681)
E58G (p.Glu58Gly) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
E58G (p.Glu58Gly) variant details
- p.Glu58Gly
- TOPMed rs931956626
- gnomAD rs931956626
- Missense
- Variant Prioritization Score for Impact Estimate 0.453
- REVEL 0.35
- MetaLR 0.42
- MetaSVM -0.48
- CADD 25.10
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available