E58D (p.Glu58Asp) variant of CD80 (P33681)
E58D (p.Glu58Asp) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
E58D (p.Glu58Asp) variant details
- p.Glu58Asp
- ExAC rs756028722
- TOPMed rs756028722
- gnomAD rs756028722
- Missense
- Variant Prioritization Score for Impact Estimate 0.15
- REVEL 0.09
- MetaLR 0.15
- MetaSVM -0.85
- CADD 15.10
- PolyPhen-2 0.29
- SIFT 0.10
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available