A60T (p.Ala60Thr) variant of CD80 (P33681)
A60T (p.Ala60Thr) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
A60T (p.Ala60Thr) variant details
- p.Ala60Thr
- TOPMed rs1390128025
- gnomAD rs1390128025
- Missense
- Variant Prioritization Score for Impact Estimate 0.0892
- REVEL 0.02
- MetaLR 0.08
- MetaSVM -1.02
- CADD 5.92
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available