S45R (p.Ser45Arg) variant of CD79A (P11912)
S45R (p.Ser45Arg) in CD79A (P11912) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
S45R (p.Ser45Arg) variant details
- p.Ser45Arg
- gnomAD 19-41879045-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- REVEL 0.17
- MetaLR 0.31
- MetaSVM -0.80
- CADD 11.60
- PolyPhen-2 0.71
- SIFT 0.35
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available