S22P (p.Ser22Pro) variant of CD79A (P11912)
S22P (p.Ser22Pro) in CD79A (P11912) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
S22P (p.Ser22Pro) variant details
- p.Ser22Pro
- gnomAD 19-41877368-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.551
- REVEL 0.45
- MetaLR 0.44
- MetaSVM -0.60
- CADD 23.70
- PolyPhen-2 0.93
- SIFT 0.18
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available