P2L (p.Pro2Leu) variant of CD79A (P11912)
P2L (p.Pro2Leu) in CD79A (P11912) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
P2L (p.Pro2Leu) variant details
- p.Pro2Leu
- cosmic curated COSV55738
- TOPMed rs2074193640
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.28
- CADD 19.80
- PolyPhen-2 0.78
- SIFT 0.07
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available