L70H (p.Leu70His) variant of CD79A (P11912)
L70H (p.Leu70His) in CD79A (P11912) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
L70H (p.Leu70His) variant details
- p.Leu70His
- gnomAD rs1555843509
- Missense
- Variant Prioritization Score for Impact Estimate 0.349
- REVEL 0.24
- CADD 18.90
- PolyPhen-2 0.83
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available