H51P (p.His51Pro) variant of CD79A (P11912)
H51P (p.His51Pro) in CD79A (P11912) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
H51P (p.His51Pro) variant details
- p.His51Pro
- rs781936282
- NCI-TCGA Cosmic COSV5573
- cosmic curated COSV55739
- ExAC rs781936282
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.11
- REVEL 0.15
- CADD 0.47
- PolyPhen-2 0.21
- SIFT 0.11
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Ashkenazi Jewish population (allele frequency 4.4e-05)
- Structural context available