G27D (p.Gly27Asp) variant of CD79A (P11912)
G27D (p.Gly27Asp) in CD79A (P11912) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
G27D (p.Gly27Asp) variant details
- p.Gly27Asp
- gnomAD 19-41878990-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- REVEL 0.54
- MetaLR 0.54
- MetaSVM -0.06
- CADD 24.30
- PolyPhen-2 0.94
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 3.1e-05)
- Structural context available
- Literature evidence available