T74K (p.Thr74Lys) variant of CD40LG (CD40 ligand)
T74K (p.Thr74Lys) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
T74K (p.Thr74Lys) variant details
- p.Thr74Lys
- gnomAD X-136650330-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.201
- REVEL 0.10
- MetaLR 0.12
- MetaSVM -0.99
- CADD 11.60
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available