T34S (p.Thr34Ser) variant of CD40LG (CD40 ligand)
T34S (p.Thr34Ser) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
T34S (p.Thr34Ser) variant details
- p.Thr34Ser
- gnomAD X-136648348-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.25
- REVEL 0.18
- MetaLR 0.15
- MetaSVM -0.98
- CADD 21.20
- PolyPhen-2 0.18
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available