T15I (p.Thr15Ile) variant of CD40LG (CD40 ligand)
T15I (p.Thr15Ile) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
T15I (p.Thr15Ile) variant details
- p.Thr15Ile
- gnomAD rs1289706273
- Missense
- Variant Prioritization Score for Impact Estimate 0.266
- REVEL 0.13
- MetaLR 0.23
- MetaSVM -0.86
- CADD 12.70
- PolyPhen-2 0.21
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 2.2e-05)
- Structural context available