T105P (p.Thr105Pro) variant of CD40LG (CD40 ligand)
T105P (p.Thr105Pro) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
T105P (p.Thr105Pro) variant details
- p.Thr105Pro
- gnomAD X-136654397-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.07
- MetaLR 0.12
- MetaSVM -1.00
- CADD 7.59
- PolyPhen-2 0.00
- SIFT 0.55
- Population evidence available
- Structural context available
- Literature evidence available