T105A (p.Thr105Ala) variant of CD40LG (CD40 ligand)
T105A (p.Thr105Ala) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
T105A (p.Thr105Ala) variant details
- p.Thr105Ala
- gnomAD X-136654397-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.05
- MetaLR 0.13
- MetaSVM -1.01
- CADD 4.85
- PolyPhen-2 0.00
- SIFT 0.80
- Population evidence available
- Structural context available
- Literature evidence available