S20N (p.Ser20Asn) variant of CD40LG (CD40 ligand)
S20N (p.Ser20Asn) in CD40LG (CD40 ligand) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S20N (p.Ser20Asn) variant details
- p.Ser20Asn
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.18
- MetaLR 0.23
- MetaSVM -0.78
- CADD 18.00
- PolyPhen-2 0.05
- SIFT 0.02
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available