R57M (p.Arg57Met) variant of CD40LG (CD40 ligand)
R57M (p.Arg57Met) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
R57M (p.Arg57Met) variant details
- p.Arg57Met
- gnomAD X-136650279-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.10
- MetaLR 0.16
- MetaSVM -0.98
- CADD 16.20
- PolyPhen-2 0.01
- SIFT 0.61
- Population evidence available
- Structural context available
- Literature evidence available