P18T (p.Pro18Thr) variant of CD40LG (CD40 ligand)
P18T (p.Pro18Thr) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
P18T (p.Pro18Thr) variant details
- p.Pro18Thr
- gnomAD X-136648300-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.14
- MetaLR 0.21
- MetaSVM -0.84
- CADD 10.80
- PolyPhen-2 0.19
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available