M66K (p.Met66Lys) variant of CD40LG (CD40 ligand)
M66K (p.Met66Lys) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
M66K (p.Met66Lys) variant details
- p.Met66Lys
- gnomAD X-136650306-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.413
- REVEL 0.36
- MetaLR 0.22
- MetaSVM -0.63
- CADD 23.40
- PolyPhen-2 0.19
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available