L41V (p.Leu41Val) variant of CD40LG (CD40 ligand)
L41V (p.Leu41Val) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
L41V (p.Leu41Val) variant details
- p.Leu41Val
- gnomAD rs1216770048
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.19
- MetaLR 0.31
- MetaSVM -0.82
- CADD 17.40
- PolyPhen-2 0.24
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available