K67R (p.Lys67Arg) variant of CD40LG (CD40 ligand)
K67R (p.Lys67Arg) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
K67R (p.Lys67Arg) variant details
- p.Lys67Arg
- gnomAD X-136650309-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.18
- MetaLR 0.17
- MetaSVM -0.97
- CADD 17.50
- PolyPhen-2 0.01
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available