I98V (p.Ile98Val) variant of CD40LG (CD40 ligand)
I98V (p.Ile98Val) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
I98V (p.Ile98Val) variant details
- p.Ile98Val
- gnomAD X-136654376-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.21
- MetaLR 0.25
- MetaSVM -0.91
- CADD 5.68
- PolyPhen-2 0.01
- SIFT 0.73
- Population evidence available
- Structural context available
- Literature evidence available