I98T (p.Ile98Thr) variant of CD40LG (CD40 ligand)
I98T (p.Ile98Thr) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
I98T (p.Ile98Thr) variant details
- p.Ile98Thr
- gnomAD X-136654377-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.17
- MetaLR 0.21
- MetaSVM -0.95
- CADD 9.61
- PolyPhen-2 0.00
- SIFT 0.54
- Population evidence available
- Structural context available
- Literature evidence available