I98M (p.Ile98Met) variant of CD40LG (CD40 ligand)
I98M (p.Ile98Met) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
I98M (p.Ile98Met) variant details
- p.Ile98Met
- cosmic curated COSV65699
- TOPMed rs2076113123
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.26
- MetaLR 0.25
- MetaSVM -0.85
- CADD 6.83
- PolyPhen-2 0.29
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 8.5e-06)
- Structural context available