I87F (p.Ile87Phe) variant of CD40LG (CD40 ligand)
I87F (p.Ile87Phe) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
I87F (p.Ile87Phe) variant details
- p.Ile87Phe
- gnomAD X-136650368-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.347
- REVEL 0.31
- MetaLR 0.29
- MetaSVM -0.21
- CADD 23.60
- PolyPhen-2 0.49
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available