I23V (p.Ile23Val) variant of CD40LG (CD40 ligand)
I23V (p.Ile23Val) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
I23V (p.Ile23Val) variant details
- p.Ile23Val
- gnomAD rs1359911582
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.25
- MetaLR 0.24
- MetaSVM -0.79
- CADD 22.00
- PolyPhen-2 0.20
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 1.9e-05)
- Structural context available