H60Y (p.His60Tyr) variant of CD40LG (CD40 ligand)
H60Y (p.His60Tyr) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
H60Y (p.His60Tyr) variant details
- p.His60Tyr
- gnomAD rs2076100370
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.08
- MetaLR 0.18
- MetaSVM -0.88
- CADD 20.20
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.9e-05)
- Structural context available