G75R (p.Gly75Arg) variant of CD40LG (CD40 ligand)
G75R (p.Gly75Arg) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G75R (p.Gly75Arg) variant details
- p.Gly75Arg
- ExAC rs771120303
- gnomAD rs771120303
- Missense
- Variant Prioritization Score for Impact Estimate 0.469
- REVEL 0.43
- MetaLR 0.27
- MetaSVM -0.56
- CADD 23.10
- PolyPhen-2 0.41
- SIFT 0.09
- Most common in the REMAINING population (allele frequency 4.4e-05)
- Structural context available